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Premarin increases the risk of developing a condition (endometrial
hyperplasia) that may lead to cancer of the lining of the uterus.
Taking progestin, another hormone drug, with Premarin lowers the risk
of developing this condition. Therefore, if your uterus has not been
removed, your doctor may prescribe a progestin for you to take
together with the estrogen. Visit your doctor regularly and report
any unusual vaginal bleeding right away.
Estrogen is a female sex hormone necessary for many processes in the
body
Premarin is used to treat symptoms of menopause; deficiency in ovary
function (including underdevelopment of female sexual characteristics
and some types of infertility); some types of breast cancer in men
and in postmenopausal women; degeneration of the vagina; and urethra
and prostate cancer. In addition, conjugated estrogens are used to
prevent osteoporosis.
Special precautions
Do not take conjugated estrogens without first talking to your doctor
if you have
a circulation, bleeding, or blood-clotting disorder;
undiagnosed, abnormal vaginal bleeding;
any type of breast, uterine, or hormone-dependent cancer
Taking conjugated estrogens may be dangerous in some cases if you
have any of the conditions listed above.
Before taking conjugated estrogens, tell your doctor if you have
high blood pressure, angina, or heart disease;
high levels of cholesterol or triglycerides in the blood;
liver disease;
kidney disease;
asthma
epilepsy
migraines
diabetes
depression
gallbladder disease
uterine fibroids;
or had a hysterectomy (uterus removed).
You may not be able to take Premarin, or you may require a dosage
adjustment or special monitoring during treatment if you have any of
the conditions listed above.
Premarin is in the FDA pregnancy category X. This means that Premarin is known to cause birth defects in an unborn baby. Do not take this medication if you are pregnant or could become pregnant during treatment.
Premarin may decrease milk flow and have other effects on milk
composition. Do not use this medication without first talking to your
doctor if you are breast-feeding a baby.
Side effects
Premarin increase the risk of developing a condition (endometrial
hyperplasia) that may lead to cancer of the lining of the uterus.
Taking progestins, another hormone drug, with Premarin lowers the
risk of developing this condition. Therefore, if your uterus has not
been removed, your doctor may prescribe a progestin for you to take
together with the estrogen. Visit your doctor regularly and report
any unusual vaginal bleeding right away.
If you experience any of the following serious side effects, stop
taking Premarin and seek emergency medical attention:
an allergic reaction (difficulty breathing; closing of the throat;
swelling of the lips, tongue, or face; or hives);
shortness or breath or pain in the chest
a painful, red, or swollen leg
abnormal vaginal bleeding
pain, swelling, or tenderness in the abdomen
severe headache or vomiting, dizziness, faintness or changes in
vision or speech
yellowing of the skin or eyes; o a lump in a breast
Other, less serious side effects may be more likely to occur.
Continue to take Premarin and talk to your doctor if you experience
decreased appetite, nausea, or vomiting
swollen or tender breasts;
acne or skin color changes
decreased sex drive
migraine headaches or dizziness
water retention (swollen hands, feet, or ankles)
problems with wearing contact lenses;
depression; or
Changes in menstrual cycle or breakthrough bleeding
Keep
all appointments with your doctor and the laboratory. Your blood
pressure should be checked regularly to determine your response to
diltiazem.
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